SciCombinator

Discover the most talked about and latest scientific content & concepts.

Journal: Journal of cardiovascular electrophysiology

25

Chagas' disease (CD) has been associated with atrial fibrillation (AF) and electrocardiographic (ECG) conduction defects. However, prior studies have shown conflicting results. We performed a meta-analysis comparing the prevalence of AF and conduction abnormalities between CD and non-CD patients.

Concepts: Epidemiology, Infectious disease, Cardiology, Heart, Atrial fibrillation, Chagas disease, Cardiac electrophysiology, Electrocardiography

25

High-risk hypertrophic cardiomyopathy (HCM) patients benefit from the implantable cardioverter defibrillator (ICD). The subcutaneous ICD (S-ICD) may provide comparable protection while avoiding the shortcomings of transvenous (TV) leads. We assessed S-ICD eligibility according to surface ECG screening test in a cohort of high-risk HCM patients.

Concepts: Implantable cardioverter-defibrillator, Cardiac electrophysiology, Hypertrophic cardiomyopathy, Ventricular fibrillation, Wearable cardioverter defibrillator

25

Left atrial(LA) interstitial fibrosis is known to have a role in the initiation and maintenance of atrial fibrillation(AF). The role of galectin-3 in the pathogenesis of cardiac fibrosis has been demonstrated in previous studies. We aimed to determine whether serum galectin-3 level is associated with markers of atrial remodeling, including the extent of LA fibrosis detected by delayed-enhancement magnetic resonance imaging(DE-MRI) and atrial electromechanical delay(AEMD) in paroxysmal AF patients with preserved left ventricular(LV) functions.

Concepts: Electromagnetism

24

The treatment of atrial tachycardia (AT) occurring after ablation for atrial fibrillation (AF) is challenging. The most common ablation strategy relies on entrainment, and electroanatomic activation mapping (EAM) using a conventional window of interest (WOI), centered on the easily detectable atrial signal on the coronary sinus catheter. We describe a novel EAM annotation technique that uses a WOI starting 40 ms prior to the P wave in order to detect the reentrant AT exit site. This WOI timing is based on the similarity between scar-related reentrant AT and scar-related ventricular tachycardia.

Concepts: Cardiology, Heart, Atrial fibrillation, Ventricular tachycardia, Supraventricular tachycardia, Tachycardia, Sinus venosus, Signal 1

24

The Sprint Fidelis defibrillator lead (Medtronic) was recalled in 2007 due to an increased risk of failure. The generator exchange (GE) procedure has been associated with the development of Fidelis lead dysfunction. The aim of this study was to compare the rate of dysfunction between Sprint Fidelis and other defibrillator leads during the first year after GE.

Concepts: Artificial pacemaker, Sprint Nextel, Medtronic

24

Intracardiac electrogram voltage remains an important metric for radiofrequency lesion application. Embedded micro-electrodes within ablation catheters are now approved for use in humans.

23

Late recovery of ablated tissue leading to reconnection of pulmonary veins remains common following radiofrequency catheter ablation for AF. Ablation Index (AI), a novel ablation quality marker, incorporates contact force (CF), time and power in a weighted formula. We hypothesized that prospective use of our previously-published derived AI targets would result in better outcomes when compared to CF-guided ablation.

Concepts: Blood, Heart, Atrial fibrillation, Management, Force

23

Ablation of scar-related ventricular tachycardia (VT), especially in non-inducible VT or hemodynamically unstable patients, can be challenging. Thus, we evaluated feasibility of an ultra high-density 3D-mapping approach to characterize the ventricular substrate and, if possible, to map VT.

Concepts: Map

22

We sought to validate a deep learning algorithm designed to predict an ejection fraction (EF) ≤ 35% based on the 12-lead electrocardiogram (ECG) in a large prospective cohort.

22

Multielectrode mapping catheters improve the ability to map within heterogeneous scar. A novel OctarayTM catheter with 8 spines and 48 electrodes may further improve the speed and resolution of atrial mapping. The aims of this study were to (1) establish the Octaray’s baseline mapping performance and electrogram characteristics in healthy atria and to (2) determine its utility for identifying gaps in a swine model of atrial ablation lines.