SciCombinator

Discover the most talked about and latest scientific content & concepts.

Journal: Chest

168

Bronchoscopy is often the initial diagnostic procedure performed in patients with pulmonary lesions suspicious for lung cancer. A bronchial genomic classifier was previously validated to identify patients at low risk for lung cancer after an inconclusive bronchoscopy. In this study, we evaluate the potential of the classifier to reduce invasive procedure utilization in patients with suspected lung cancer.

Concepts: Epidemiology, Cancer, Pulmonology, Lung cancer, Cancer staging, Pneumonia, Bronchoscopy, Alveolar duct

103

Urine output (UO) is a vital sign for critical ill patients but standards for monitoring and reporting vary widely between ICUs. Careful monitoring of UO could lead to earlier recognition of acute kidney injury (AKI) and better fluid management. We sought to determine if intensity of UO monitoring is associated with outcomes in patients with and without AKI.

Concepts: Blood pressure, Vital signs, Acute kidney injury, Medical signs

78

Coronavirus disease-2019 (COVID-19) is sweeping the globe. Despite multiple case-series, actionable knowledge to proactively tailor decision-making is missing.

72

We update recommendations on 12 topics that were in the 9th edition of these guidelines, and address 3 new topics.

Concepts: Medicine, Cure

61

In COPD, functional status is improved by pulmonary rehabilitation (PR) but requires specific facilities. Tai Chi, which combines psychological treatment and physical exercise and requires no special equipment, is widely practiced in China and is becoming increasingly popular in the rest of the world. We hypothesized that Tai Chi is equivalent (ie, difference less than ±4 St. George’s Respiratory Questionnaire [SGRQ] points) to PR.

Concepts: Randomized controlled trial, Physical exercise, World

60

The global burden of sepsis is estimated as 15 to 19 million cases annually with a mortality rate approaching 60% in low income countries.

Concepts: Systemic inflammatory response syndrome, Vitamin, Septic shock, Sepsis

53

Lung nodules are a diagnostic challenge with an estimated yearly incidence of 1.6 million in the United States. This study evaluated the accuracy of an integrated proteomic classifier in identifying benign nodules in patients with a pretest probability of malignancy (pCA) ≤50%.

Concepts: Cancer, Medical terms, United States, United States Constitution, Poverty in the United States, U.S. state, Solitary pulmonary nodule, Chinese language

50

Chest x-ray (CXR) is the test of choice for diagnosing pneumonia. Lung ultrasound (LUS) has been shown to be accurate for diagnosing pneumonia in children and may be an alternative to CXR. Our objective was to determine the feasibility and safety of substituting LUS for CXR when evaluating children with suspected pneumonia.

Concepts: Epidemiology, Lung, Pneumonia, Heart, Randomized controlled trial, Free will

48

Emerging evidence shows that severe COVID-19 can be complicated by a significant coagulopathy, that likely manifests in the form of both microthrombosis and venous thromboembolism (VTE). This recognition has led to the urgent need for practical guidance regarding prevention, diagnosis, and treatment of VTE.

43

Over a quarter of the US population qualify as excessive alcohol consumers. Alcohol use impacts several lung diseases and heavy consumption has been associated with poor clinical outcomes. The fractional excretion of exhaled nitric oxide (FeNO) has clinical implications in multiple airway diseases. We hypothesized that excessive alcohol intake is associated with lower FeNO levels.

Concepts: Epidemiology, Pulmonology, Poverty, Nitric oxide, Alcoholic beverage, Beer, Exhaled nitric oxide, French Quarter