Discover the most talked about and latest scientific content & concepts.

Concept: Behaviour therapy


Web-based cognitive-behavioral therapeutic (CBT) apps have demonstrated efficacy but are characterized by poor adherence. Conversational agents may offer a convenient, engaging way of getting support at any time.

Concepts: Posttraumatic stress disorder, Schizophrenia, Psychotherapy, Major depressive disorder, Behaviour therapy, Psychology, Randomized controlled trial, Cognitive behavioral therapy



The Dutch Fatigue In Teenagers on the interNET (FITNET) study claimed that after 6 months, internet based cognitive behaviour therapy in adolescents with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), led to a 63% recovery rate compared to 8% after usual care, and that this was maintained at long term follow up (LTFU). Our reanalysis shows that their post-hoc definition of recovery included the severely ill, the unblinded trial had no adequate control group and it used lax selection criteria as well as outcomes assessed via questionnaires rather than objective outcomes, further contributing to exaggerated recovery figures. Their decision not to publish the actometer results might suggest that these did not back their recovery claims. Despite these bias creating methodological faults, the trial still found no significant difference in recovery rates (“~60%”) at LTFU, the trial’s primary goal. This is similar to or worse than the documented 54-94% spontaneous recovery rates within 3-4 years, suggesting that both FITNET and usual care (consisting of cognitive behaviour and graded exercise therapies) are ineffective and might even impede natural recovery in adolescents with ME/CFS. This has implications for the upcoming costly NHS FITNET trial which is a blueprint of the Dutch study, exposing it to similar biases.

Concepts: History of the Internet, Psychology, Behaviour therapy, Scientific method, Behaviorism, Internet, Chronic fatigue syndrome, Cognitive behavioral therapy


A randomised control trial (RCT) was conducted to examine the efficacy of couple-based cognitive behaviour therapy (CBT) for Premenstrual Disorders (PMDs), in comparison to one-to-one CBT and a wait-list control.

Concepts: Pharmaceutical industry, Experimental design, Psychotherapy, Behaviour therapy, Efficacy, Epidemiology, Cognitive behavioral therapy, Randomized controlled trial


Up to 21% of adults will develop tinnitus, which is one of the most distressing and debilitating audiological problems. The absence of medical cures and standardised practice can lead to costly and prolonged treatment. We aimed to assess effectiveness of a stepped-care approach, based on cognitive behaviour therapy, compared with usual care in patients with varying tinnitus severity.

Concepts: Medicine, Behaviour therapy, Clinical trial, Health care, Behaviorism, Cognitive behavioral therapy, Randomized controlled trial


This article describes a 10-session cognitive-behavioral therapy (CBT) used in a randomized controlled trial with people with anxiety and mild-to-moderate dementia. The aim of the therapy is to reduce symptoms of anxiety by increasing a sense of safety and self-efficacy. The therapy is characterized by a person-centered approach to CBT, using individual tailoring to accommodate for cognitive deficits and other challenges. Three phases of therapy are described: (a) socialization to model (including overcoming barriers to participation), goal setting, and formulation; (b) application of cognitive and behavioral change techniques to address unhelpful autonomic reactions, “strategic” reactions, “rules for living,” and interpersonal aspects; and © consolidation and ending in the context of chronic, deteriorating illness. The approach prioritizes direct work with the person with dementia, with the involvement of a “supportive other” where available and when necessary. The protocol is designed for use by therapists with prior experience in CBT.

Concepts: Posttraumatic stress disorder, Clinical psychology, Behaviour therapy, Major depressive disorder, Cognitive therapy, Psychotherapy, Psychology, Cognitive behavioral therapy


This randomized controlled study compared acceptance and commitment therapy (ACT), cognitive-behavioral therapy (CBT), and a control group.

Concepts: Behaviorism, Psychotherapy, Mindfulness, Behaviour therapy, Cognitive behavioral therapy


To compare the efficacy of telephone-delivered cognitive-behavioral therapy for insomnia to an information pamphlet control on sleep and daytime functioning at pretreatment, posttreatment, and 12-wk follow-up.

Concepts: Clinical psychology, Psychotherapy, Behaviour therapy, Randomized controlled trial, Cognitive behavioral therapy, Generalized anxiety disorder, Zopiclone


This pilot study examined the feasibility, safety, and effectiveness of using an online computerized cognitive behavioral therapy (CBT) for treating Chinese patients with depression.

Concepts: Behaviour therapy, Behaviorism, Psychology, Cognitive behavioral therapy


Anxiety and depression in children and adolescents are undertreated. Computer- and Internet-based cognitive behavioral treatments (cCBT) may be an attractive treatment alternative to regular face-to-face treatment.This meta-analysis aims to evaluate whether cCBT is effective for treating symptoms of anxiety and depression in youth.

Concepts: Posttraumatic stress disorder, Schizophrenia, Panic disorder, Psychotherapy, Major depressive disorder, Behaviour therapy, Psychology, Cognitive behavioral therapy