Discover the most talked about and latest scientific content & concepts.

Concept: Article


Catastrophizing is an exaggerated negative evaluation and attention to specific symptoms such as pain or fatigue. A number of studies consistently support the significant role of catastrophizing in pain. However, the role of catastrophizing in fatigue is less frequently investigated. This article provides a critical review of published studies investigating this association.

Concepts: Symptom, Fatigue, Post-concussion syndrome, Critical path method, Grammatical number, Article


Article-level metrics (ALMs) provide a wide range of metrics about the uptake of an individual journal article by the scientific community after publication. They include citations, usage statistics, discussions in online comments and social media, social bookmarking, and recommendations. In this essay, we describe why article-level metrics are an important extension of traditional citation-based journal metrics and provide a number of example from ALM data collected for PLOS Biology.

Concepts: Scientific method, Mathematics, Writing, The UpTake, Article, Essay, Alms


In this article, we use our experiences to provide tips for contacting potential supervisors, what to expect from them and how to approach them for research opportunities. With appropriate planning, you will be surprised by the number of prestigious academics who would be willing for you to join their research group, and to get you involved in a research project.

Concepts: Research, Article


Although global efforts in the past decade have halved the number of deaths due to malaria, there are still an estimated 219 million cases of malaria a year, causing more than half a million deaths. In this forum article, we asked experts working in malaria research and control to discuss the ways in which malaria might eventually be eradicated. Their collective views highlight the challenges and opportunities, and explain how multi-factorial and integrated processes could eventually make malaria eradication a reality.

Concepts: Mathematics, Malaria, Article


This Essay from Nicola Low and colleagues discusses the importance of the nucleic acid amplification tests for rapid detection of N. gonorrhoeae and its resistance determinants, as well as the importance of ensuring their rational use, as priorities for controlling both gonorrhoea and antimicrobial resistance. Please see later in the article for the Editors' Summary.

Concepts: DNA, Nucleic acid, Writing, Neisseria gonorrhoeae, Gonorrhea, Article, Editors, Mercury Prize


The number of citations received is considered an index of study quality and impact. We aimed to examine the factors associated with the number of citations of published articles, focusing on the article length.

Concepts: Index Librorum Prohibitorum, Grammatical number, Article


This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online at . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from .Originally published in the Annual Update in Intensive Care and Emergency Medicine 2017. The number of authors differs in the two versions due to constraints regarding the number of authors in the Annual Update in Intensive Care and Emergency Medicine. In the Annual Update version of the review, the three senior authors appear in the acknowledgement section. In the Critical Care version, these three senior authors appear as full authors of the manuscript. All authors helped draft and revise the manuscript for critical intellectual content.

Concepts: Intensive care medicine, Version, Article


Since September 2005, the International Committee of Medical Journal Editors (ICMJE) has required that randomised controlled trials (RCTs) are prospectively registered in a publicly accessible database. After registration, a trial registration number (TRN) is assigned to each RCT, which should make it easier to identify future publications and cross-check published results with associated registry entries, as long as the unique identification number is reported in the article.

Concepts: Randomized controlled trial,, Identification, Grammatical number, Article


To 1) estimate the number of Parties to the Framework Convention on Tobacco Control (FCTC) providing tobacco dependence treatment in accordance with the recommendations of Article 14 and its guidelines; 2) assess association between provision and countries' income level; and 3) assess progress over time.

Concepts: Mathematics, World Health Organization, Convention, Household income in the United States, Grammatical number, Article, Tobacco control, World Health Organization Framework Convention on Tobacco Control


Malaria in the Asia-Pacific region has been targeted for elimination by the year 2030. This article asks the question, “by what means?” in the context of proven technical strategies and tools against key challenges imposed by the distinct character of the Asia-Pacific malaria problem. The misperception of malaria in the Asia-Pacific region as a less serious but otherwise essentially similar problem to African malaria lulls us into rote application of the same tools and strategies. Those now mitigating the harm done by malaria in Africa will not suffice to eliminate malaria in the Asia-Pacific region - these tasks and the problems are fundamentally distinct. This article describes the singular characteristics of Asia-Pacific malaria and the bearing of those upon the technical strategy of malaria elimination. Most of the tools needed for that endeavor do not yet exist and spirited calls for elimination within the next 14 years may discourage the patience and investments needed to conceive, optimize and validate them.

Concepts: Malaria, Africa, Question, Strategy, Problem, Article, Asia-Pacific, Strategy pattern