Anesthesia and analgesia | 11 Oct 2013
BM Ilfeld, N Malhotra, TJ Furnish, MC Donohue and SJ Madison
Currently available local anesthetics approved for single-injection peripheral nerve blocks have a maximum duration of <24 hours. A liposomal bupivacaine formulation (EXPAREL, Pacira Pharmaceuticals, Inc., San Diego, CA), releasing bupivacaine over 96 hours, recently gained Food and Drug Administration approval exclusively for wound infiltration but not peripheral nerve blocks.
* Data courtesy of Altmetric.com