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BM Ilfeld, N Malhotra, TJ Furnish, MC Donohue and SJ Madison
Abstract
Currently available local anesthetics approved for single-injection peripheral nerve blocks have a maximum duration of <24 hours. A liposomal bupivacaine formulation (EXPAREL, Pacira Pharmaceuticals, Inc., San Diego, CA), releasing bupivacaine over 96 hours, recently gained Food and Drug Administration approval exclusively for wound infiltration but not peripheral nerve blocks.
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Concepts
Local anesthesia, Peripheral nervous system, Block, Anesthesia, Pharmacology, Local anesthetic, Nerve block
MeSH headings
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