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C Ballard, E Jones, N Gauge, D Aarsland, OB Nilsen, BK Saxby, D Lowery, A Corbett, K Wesnes, E Katsaiti, J Arden, D Amaoko, N Prophet, B Purushothaman and D Green
Abstract
The study determined the one year incidence of post operative cognitive decline (POCD) and evaluated the effectiveness of an intra-operative anaesthetic intervention in reducing post-operative cognitive impairment in older adults (over 60 years of age) undergoing elective orthopaedic or abdominal surgery. METHODS AND TRIAL DESIGN: The design was a prospective cohort study with a nested randomised, controlled intervention trial, using intra-operative BiSpectral index and cerebral oxygen saturation monitoring to enable optimisation of anaesthesia depth and cerebral oxygen saturation in older adults undergoing surgery.
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Concepts
Photosynthesis, Experimental design, Cohort study, Surgery, Randomized controlled trial, Epidemiology, Anesthesia, Clinical trial
MeSH headings
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