Optimised anaesthesia to reduce post operative cognitive decline (POCD) in older patients undergoing elective surgery, a randomised controlled trial.
OPEN PloS one | 21 Jun 2012
C Ballard, E Jones, N Gauge, D Aarsland, OB Nilsen, BK Saxby, D Lowery, A Corbett, K Wesnes, E Katsaiti, J Arden, D Amaoko, N Prophet, B Purushothaman and D Green
The study determined the one year incidence of post operative cognitive decline (POCD) and evaluated the effectiveness of an intra-operative anaesthetic intervention in reducing post-operative cognitive impairment in older adults (over 60 years of age) undergoing elective orthopaedic or abdominal surgery. METHODS AND TRIAL DESIGN: The design was a prospective cohort study with a nested randomised, controlled intervention trial, using intra-operative BiSpectral index and cerebral oxygen saturation monitoring to enable optimisation of anaesthesia depth and cerebral oxygen saturation in older adults undergoing surgery.
* Data courtesy of Altmetric.com