Vaccine failure and serologic response to live attenuated and inactivated influenza vaccines in children during the 2013-2014 season
Vaccine | 6 Feb 2018
JP King, HQ McLean, JK Meece, MZ Levine, SM Spencer, B Flannery and EA Belongia
Recent observational studies in the United States indicated live attenuated influenza vaccine (LAIV) was less effective in children against clinical influenza infection caused by A(H1N1)pdm09 relative to inactivated influenza vaccine (IIV). During the 2013-2014 influenza season, we conducted an observational study among children aged 5-17 years to compare serologic responses to LAIV and IIV and explore factors associated with vaccine failure.
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