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JT Smilowitz, J Moya, MA Breck, C Cook, A Fineberg, K Angkustsiri and MA Underwood
Abstract
Historically, bifidobacteria were the dominant intestinal bacteria in breastfed infants. Still abundant in infants in developing nations, levels of intestinal bifidobacteria are low among infants in developed nations. Recent studies have described an intimate relationship between human milk and a specific subspecies of Bifidobacterium, B. longum subsp. infantis (B. infantis), yet supplementation of breastfed, healthy, term infants with this organism, has not been reported. The IMPRINT Study, a Phase I clinical trial, was initiated to determine the safety and tolerability of supplementing breastfed infants with B. infantis (EVC001).
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Concepts
Interpersonal relationship, Immune system, Developed country, Bifidobacterium, Developing country, Species, Gut flora, Bacteria
MeSH headings
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