Effectiveness of live attenuated influenza vaccine and inactivated influenza vaccine in children during the 2014-2015 season
OPEN Vaccine | 15 Apr 2017
HQ McLean, H Caspard, MR Griffin, KA Poehling, M Gaglani, EA Belongia, HK Talbot, TR Peters, K Murthy and CS Ambrose
A clinical study found that live attenuated influenza vaccine (LAIV) was superior to inactivated influenza vaccine (IIV) against drifted A(H3N2) viruses in children. During the 2014-2015 influenza season, widespread circulation of antigenically and genetically drifted A(H3N2) viruses provided an opportunity to evaluate subtype-specific vaccine effectiveness (VE) of quadrivalent LAIV (LAIV4) and IIV in children.
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