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Abstract
Major depressive disorder may be due to psychoneuroimmunological dysfunction, as studies have documented increased levels of a variety of inflammatory mediators in depressed subjects. Nitric oxide (NO) is marker of inflammation, and fractional exhaled NO (FeNO) is a marker of airway inflammation. Plasma NO and FeNO levels have been shown to be lower in subjects with depression in small studies. We sought to assess the association of depression with C-reactive protein (CRP) and FeNO levels in a large and representative sample of the US population.
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Concepts
Exhaled nitric oxide, Nitric oxide, Bipolar disorder, Types of psychological depression, Seasonal affective disorder, Inflammation, Major depressive disorder, C-reactive protein
MeSH headings
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