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M Versini, PY Jeandel, T Bashi, G Bizzaro, M Blank and Y Shoenfeld
Abstract
The Hygiene Hypothesis (HH) attributes the dramatic increase in autoimmune and allergic diseases observed in recent decades in Western countries to the reduced exposure to diverse immunoregulatory infectious agents. This theory has since largely been supported by strong epidemiological and experimental evidence.
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Concepts
Epidemiology, Hygiene hypothesis, Hypothesis, Immune system, Infectious disease
MeSH headings
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