OPEN PloS one | 19 Mar 2015
T Sathyapalan, NJ Thatcher, R Hammersley, AS Rigby, A Pechlivanis, NJ Gooderham, E Holmes, CW le Roux, SL Atkin and F Courts
Aspartame is a commonly used intense artificial sweetener, being approximately 200 times sweeter than sucrose. There have been concerns over aspartame since approval in the 1980s including a large anecdotal database reporting severe symptoms. The objective of this study was to compare the acute symptom effects of aspartame to a control preparation.
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